Here is who is most likely to win their first Oscar at this year’s ceremony: Kieran Culkin is nominated for Best Supporting Actor for his performance in Jesse Eisenberg’s movie, “A Real Pain.” This is a first-ever Oscar nomination for Culkin and he will most likely take home the Academy Award.

Andrew Garfield and Jesse Eisenberg arrive at the Vanity Fair Oscar Party on Sunday, March 2, 2025, at the Wallis Annenberg Center for the Performing Arts in Beverly Hills, Calif.

The 97th Academy Awards have kicked off at the Dolby Theatre in Los Angeles and there have already been many “firsts” achieved in the show. “Emilia Pérez” leads the pack with 13 Oscar nominations, but “Wicked” and “The Brutalist” are close behind.

Kieran Culkin took home the Oscar for Best Supporting Actor at the 2025 Academy Awards for his role as Benji Kaplan in Jesse Eisenberg's A Real Pain. In A Real Pain, Culkin and Eisenberg play an odd-couple cousin pairing on a trip around their grandmother's native Poland.

Stars including Ariana Grande, Cynthia Erivo, Jesse Eisenberg, Conan O'Brien and Edward Norton walk the red carpet at the 2025 Academy Awards.

Macaulay Culkin celebrated his brother Kieran Culkin's win at the 97th Academy Awards for his supporting role in Jesse Eisenberg's A Real Pain. When speaking at the Vanity Fair Oscars party on the red carpet,

The actors, who starred as frenemies Eduardo Saverin and Mark Zuckerberg, hugged and posed for photos together at the Vanity Fair Oscars after-party.Almost 15 years after the release of The Social Network,

Andrew Garfield and Jesse Eisenberg reunited on the 2025 Vanity Fair Oscar Party red carpet nearly 15 years after starring in 'The Social Network'

"I am riding the coattails of her goodwill," Eisenberg said when accepting the best screenplay award on Saturday.

Jesse Eisenberg called actress Emma Stone his "fairy godmother" during his acceptance speech for best screenplay at the 2025 Film Independent Spirit Awards, as per The Hollywood Reporter.The Social Network actor won the best screenplay award for his film The Real Pain,